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C78.89 vs C88.01

C78.89 (Secondary malignant neoplasm of other digestive organs) compared with C88.01 (Waldenström macroglobulinemia, in remission), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. C88.01 carries an Excludes2 note covering C78.89: “secondary neoplasm of spleen (C78.89)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

C78.89Secondary malignant neoplasm of other digestive organsC88.01Waldenström macroglobulinemia, in remission
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionSecondary malignant neoplasm of other digestive organs is a billable ICD-10-CM diagnosis code (C78.89).Waldenström macroglobulinemia, in remission is a billable ICD-10-CM diagnosis code (C88.01).

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources