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C79.52 vs C81.29

C79.52 (Secondary malignant neoplasm of bone marrow) compared with C81.29 (Mixed cellularity Hodgkin lymphoma, extranodal and solid organ sites), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Relationship

Informational

Excludes2 relationship

C81.29
Mixed cellularity Hodgkin lymphoma, extranodal and solid organ sites
C79.52
Secondary malignant neoplasm of bone marrow

Distinct conditions — both may be reported.

“secondary neoplasm of bone marrow (C79.52)”

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source: CMS ICD-10-CM tabular instructional notes

Can these codes be reported together?

Yes, when both are documented. C81.29 carries an Excludes2 note covering C79.52: “secondary neoplasm of bone marrow (C79.52)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

C79.52Secondary malignant neoplasm of bone marrowC81.29Mixed cellularity Hodgkin lymphoma, extranodal and solid organ sites
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionSecondary malignant neoplasm of bone marrow is a billable ICD-10-CM diagnosis code (C79.52).Mixed cellularity Hodgkin lymphoma, extranodal and solid organ sites is a billable ICD-10-CM diagnosis code (C81.29).

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources