C81.21 vs Z85.71
C81.21 (Mixed cellularity Hodgkin lymphoma, lymph nodes of head, face, and neck) compared with Z85.71 (Personal history of Hodgkin lymphoma), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. C81.21 carries an Excludes1 note covering Z85.71: “personal history of Hodgkin lymphoma (Z85.71)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| C81.21Mixed cellularity Hodgkin lymphoma, lymph nodes of head, face, and neck | Z85.71Personal history of Hodgkin lymphoma | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | C00-D49 — Neoplasms (C00-D49) | Z00-Z99 — Factors Influencing Health Status and Contact with Health Services (Z00-Z99) |
| Definition | Mixed cellularity Hodgkin lymphoma, lymph nodes of head, face, and neck is a billable ICD-10-CM diagnosis code (C81.21). | Personal history of Hodgkin lymphoma is a billable ICD-10-CM diagnosis code (Z85.71). |
| Includes | — | Conditions classifiable to C81 |
| Use additional code | — | code to identify: alcohol use and dependence (F10.-) exposure to environmental tobacco smoke (Z77.22) |
| Code first | — | any follow-up examination after treatment of malignant neoplasm (Z08) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources