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C92.1 vs C92.2

C92.1 (Chronic myeloid leukemia, BCR/ABL-positive) compared with C92.2 (Atypical chronic myeloid leukemia, BCR/ABL-negative), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. C92.1 carries an Excludes1 note covering C92.2: “atypical chronic myeloid leukemia BCR/ABL-negative (C92.2-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

C92.1Chronic myeloid leukemia, BCR/ABL-positiveC92.2Atypical chronic myeloid leukemia, BCR/ABL-negative
Billing statusNon-billable header

Report instead: C92.10, C92.11, C92.12

Non-billable header

Report instead: C92.20, C92.21, C92.22

ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionChronic myeloid leukemia, BCR/ABL-positive is a non-billable ICD-10-CM category code (C92.1).Atypical chronic myeloid leukemia, BCR/ABL-negative is a non-billable ICD-10-CM category code (C92.2).
Includes
granulocytic leukemia
myelogenous leukemia
Chronic myelogenous leukemia, Philadelphia chromosome (Ph1) positive
Chronic myelogenous leukemia, t(9;22) (q34;q11)
granulocytic leukemia
myelogenous leukemia

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources