C96.0 vs C96.5
C96.0 (Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis) compared with C96.5 (Multifocal and unisystemic Langerhans-cell histiocytosis), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. C96.0 carries an Excludes1 note covering C96.5: “multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
No — do not report together. C96.5 carries an Excludes1 note covering C96.0: “multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis (C96.0)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| C96.0Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis | C96.5Multifocal and unisystemic Langerhans-cell histiocytosis | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis is a billable ICD-10-CM diagnosis code (C96.0). | Multifocal and unisystemic Langerhans-cell histiocytosis is a billable ICD-10-CM diagnosis code (C96.5). |
| Includes | Histiocytosis X, multisystemic Letterer-Siwe disease | Hand-Schüller-Christian disease Histiocytosis X, multifocal |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources