C96.0 vs C96.6
C96.0 (Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis) compared with C96.6 (Unifocal Langerhans-cell histiocytosis), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. C96.0 carries an Excludes1 note covering C96.6: “unifocal Langerhans-cell histiocytosis (C96.6)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
No — do not report together. C96.6 carries an Excludes1 note covering C96.0: “multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| C96.0Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis | C96.6Unifocal Langerhans-cell histiocytosis | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis is a billable ICD-10-CM diagnosis code (C96.0). | Unifocal Langerhans-cell histiocytosis is a billable ICD-10-CM diagnosis code (C96.6). |
| Includes | Histiocytosis X, multisystemic Letterer-Siwe disease | Eosinophilic granuloma Histiocytosis X, unifocal Histiocytosis X NOS Langerhans-cell histiocytosis NOS |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources