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C96.29 vs D89.42

C96.29 (Other malignant mast cell neoplasm) compared with D89.42 (Idiopathic mast cell activation syndrome), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D89.42 carries an Excludes1 note covering C96.29: “malignant mast cell neoplasm (C96.2-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

No — do not report together. D89.42 carries an Excludes1 note covering C96.29: “malignant mastocytoma (C96.29)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

C96.29Other malignant mast cell neoplasmD89.42Idiopathic mast cell activation syndrome
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionOther malignant mast cell neoplasm is a billable ICD-10-CM diagnosis code (C96.29).Idiopathic mast cell activation syndrome is a billable ICD-10-CM diagnosis code (D89.42).
Includes
defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources