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Compare/C96.5 vs D76

C96.5 vs D76

C96.5 (Multifocal and unisystemic Langerhans-cell histiocytosis) compared with D76 (Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D76 carries an Excludes1 note covering C96.5: “Hand-Schüller-Christian disease (C96.5)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

No — do not report together. D76 carries an Excludes1 note covering C96.5: “histiocytosis X, multifocal (C96.5)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

No — do not report together. D76 carries an Excludes1 note covering C96.5: “Langerhans-cell histiocytosis, multifocal (C96.5)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

C96.5Multifocal and unisystemic Langerhans-cell histiocytosisD76Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
Billing statusBillableNon-billable header

Report instead: D76.1, D76.2, D76.3

ClassificationC00-D49 — Neoplasms (C00-D49)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionMultifocal and unisystemic Langerhans-cell histiocytosis is a billable ICD-10-CM diagnosis code (C96.5).Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue is a non-billable ICD-10-CM category code (D76).
Includes
Hand-Schüller-Christian disease
Histiocytosis X, multifocal

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources