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Compare/D43 vs D48.2

D43 vs D48.2

D43 (Neoplasm of uncertain behavior of brain and central nervous system) compared with D48.2 (Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D43 carries an Excludes1 note covering D48.2: “neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D43Neoplasm of uncertain behavior of brain and central nervous systemD48.2Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
Billing statusNon-billable header

Report instead: D43.0, D43.1, D43.2, D43.3, D43.4

Billable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionNeoplasm of uncertain behavior of brain and central nervous system is a non-billable ICD-10-CM category code (D43).Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system is a billable ICD-10-CM diagnosis code (D48.2).

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources