Skip to main content
Compare/D46 vs D61.81

D46 vs D61.81

D46 (Myelodysplastic syndromes) compared with D61.81 (Pancytopenia), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. D61.81 carries an Excludes2 note covering D46: “pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

D46Myelodysplastic syndromesD61.81Pancytopenia
Billing statusNon-billable header

Report instead: D46.0, D46.1, D46.20, D46.21, D46.22

Non-billable header

Report instead: D61.810, D61.811, D61.818

ClassificationC00-D49 — Neoplasms (C00-D49)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionMyelodysplastic syndromes is a non-billable ICD-10-CM category code (D46).Pancytopenia is a non-billable ICD-10-CM category code (D61.81).
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
—
Edit this comparisonCheck a whole claim

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources