D53 vs E51

D53 (Other nutritional anemias) compared with E51 (Thiamine deficiency), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. E51 carries an Excludes2 note covering D53: “nutritional anemias (D50-D53)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

	D53Other nutritional anemias	E51Thiamine deficiency
Billing status	Non-billable header Report instead: D53.0, D53.1, D53.2, D53.8, D53.9	Non-billable header Report instead: E51.11, E51.12, E51.2, E51.8, E51.9
Classification	D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)	E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)
Definition	Other nutritional anemias is a non-billable ICD-10-CM category code (D53).	Thiamine deficiency is a non-billable ICD-10-CM category code (E51).
Includes	megaloblastic anemia unresponsive to vitamin B12 or folate therapy	—

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Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources