Skip to main content
Compare/D55 vs E87

D55 vs E87

D55 (Anemia due to enzyme disorders) compared with E87 (Other disorders of fluid, electrolyte and acid-base balance), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. E87 carries an Excludes1 note covering D55: “hemolytic anemias attributable to enzyme disorders (D55.-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D55Anemia due to enzyme disordersE87Other disorders of fluid, electrolyte and acid-base balance
Billing statusNon-billable header

Report instead: D55.0, D55.1, D55.21, D55.29, D55.3

Non-billable header

Report instead: E87.0, E87.1, E87.20, E87.21, E87.22

ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)
DefinitionAnemia due to enzyme disorders is a non-billable ICD-10-CM category code (D55).Other disorders of fluid, electrolyte and acid-base balance is a non-billable ICD-10-CM category code (E87).

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources