D59.5 vs R82.3
D59.5 (Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]) compared with R82.3 (Hemoglobinuria), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. D59.5 carries an Excludes1 note covering R82.3: “hemoglobinuria NOS (R82.3)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
No — do not report together. R82.3 carries an Excludes1 note covering D59.5: “hemoglobinuria due to paroxysmal nocturnal [Marchiafava-Micheli] (D59.5)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| D59.5Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli] | R82.3Hemoglobinuria | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) | R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99) |
| Definition | Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli] is a billable ICD-10-CM diagnosis code (D59.5). | Hemoglobinuria is a billable ICD-10-CM diagnosis code (R82.3). |
| Includes | — | chromoabnormalities in urine |
| Use additional code | — | code to identify any retained foreign body, if applicable (Z18.-) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources