D61.01 vs D61.81
D61.01 (Constitutional (pure) red blood cell aplasia) compared with D61.81 (Pancytopenia), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. D61.81 carries an Excludes1 note covering D61.01: “pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| D61.01Constitutional (pure) red blood cell aplasia | D61.81Pancytopenia | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) | D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) |
| Definition | Constitutional (pure) red blood cell aplasia is a billable ICD-10-CM diagnosis code (D61.01). | Pancytopenia is a non-billable ICD-10-CM category code (D61.81). |
| Includes | Blackfan-Diamond syndrome Congenital (pure) red cell aplasia Familial hypoplastic anemia Primary (pure) red cell aplasia | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources