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Compare/D68.4 vs P53

D68.4 vs P53

D68.4 (Acquired coagulation factor deficiency) compared with P53 (Hemorrhagic disease of newborn), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D68.4 carries an Excludes1 note covering P53: “vitamin K deficiency of newborn (P53)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D68.4Acquired coagulation factor deficiencyP53Hemorrhagic disease of newborn
Billing statusBillableBillable
ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)P00-P96 — Certain Conditions Originating in the Perinatal Period (P00-P96)
DefinitionAcquired coagulation factor deficiency is a billable ICD-10-CM diagnosis code (D68.4).Hemorrhagic disease of newborn is a billable ICD-10-CM diagnosis code (P53).
Includes
Deficiency of coagulation factor due to liver disease
Deficiency of coagulation factor due to vitamin K deficiency
Vitamin K deficiency of newborn

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources