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D72.18 vs D80

D72.18 (Eosinophilia in diseases classified elsewhere) compared with D80 (Immunodeficiency with predominantly antibody defects), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D72.18 carries an Excludes1 note covering D80: “immunity disorders (D80-D89)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D72.18Eosinophilia in diseases classified elsewhereD80Immunodeficiency with predominantly antibody defects
Billing statusBillableNon-billable header

Report instead: D80.0, D80.1, D80.2, D80.3, D80.4

ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionEosinophilia in diseases classified elsewhere is a billable ICD-10-CM diagnosis code (D72.18).Immunodeficiency with predominantly antibody defects is a non-billable ICD-10-CM category code (D80).
Includes
defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis
Code first
underlying disease, such as:
chronic myelomonocytic leukemia (C93.1-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources