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Compare/D73.0 vs Z90.81

D73.0 vs Z90.81

D73.0 (Hyposplenism) compared with Z90.81 (Acquired absence of spleen), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D73.0 carries an Excludes1 note covering Z90.81: “postsurgical absence of spleen (Z90.81)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D73.0HyposplenismZ90.81Acquired absence of spleen
Billing statusBillableBillable
ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)Z00-Z99 — Factors Influencing Health Status and Contact with Health Services (Z00-Z99)
DefinitionHyposplenism is a billable ICD-10-CM diagnosis code (D73.0).Acquired absence of spleen is a billable ICD-10-CM diagnosis code (Z90.81).
Includes
Atrophy of spleen
postprocedural or post-traumatic loss of body part NEC

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources