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Compare/D73.1 vs D73.81

D73.1 vs D73.81

D73.1 (Hypersplenism) compared with D73.81 (Neutropenic splenomegaly), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D73.1 carries an Excludes1 note covering D73.81: “neutropenic splenomegaly (D73.81)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

No — do not report together. D73.1 carries an Excludes1 note covering D73.81: “primary splenic neutropenia (D73.81)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D73.1HypersplenismD73.81Neutropenic splenomegaly
Billing statusBillableBillable
ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionHypersplenism is a billable ICD-10-CM diagnosis code (D73.1).Neutropenic splenomegaly is a billable ICD-10-CM diagnosis code (D73.81).
Includes
Werner-Schultz disease

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources