D89.831 vs T86
D89.831 (Cytokine release syndrome, grade 1) compared with T86 (Complications of transplanted organs and tissue), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. D89.831 carries an Excludes2 note covering T86: “transplant failure and rejection (T86.-)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Sequencing on the claim
1stT86 then D89.831
D89.831 carries a Code First instruction covering T86: “complications of transplanted organs and tissue (T86.-)”
Side by side
| D89.831Cytokine release syndrome, grade 1 | T86Complications of transplanted organs and tissue | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Cytokine release syndrome, grade 1 is a billable ICD-10-CM diagnosis code (D89.831). | Complications of transplanted organs and tissue is a non-billable ICD-10-CM category code (T86). |
| Includes | defects in the complement system immunodeficiency disorders, except human immunodeficiency virus [HIV] disease sarcoidosis | — |
| Use additional code | code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5) code to identify associated manifestations | code to identify other transplant complications, such as: graft-versus-host disease (D89.81-) malignancy associated with organ transplant (C80.2) |
| Code first | underlying cause, such as: complications following infusion, transfusion and therapeutic injection (T80.89-) | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources