E08 vs N16
E08 (Diabetes mellitus due to underlying condition) compared with N16 (Renal tubulo-interstitial disorders in diseases classified elsewhere), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. N16 carries an Excludes1 note covering E08: “renal tubular degeneration in diabetes (E08-E13 with .29)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| E08Diabetes mellitus due to underlying condition | N16Renal tubulo-interstitial disorders in diseases classified elsewhere | |
|---|---|---|
| Billing status | Non-billable header | Billable |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | N00-N99 — Diseases of the Genitourinary System (N00-N99) |
| Definition | Diabetes mellitus due to underlying condition is a non-billable ICD-10-CM category code (E08). | Renal tubulo-interstitial disorders in diseases classified elsewhere is a billable ICD-10-CM diagnosis code (N16). |
| Includes | — | pyelonephritis Pyelonephritis Tubulo-interstitial nephritis |
| Use additional code | code to identify control using: injectable non-insulin antidiabetic drugs (Z79.85) insulin (Z79.4) | — |
| Code first | the underlying condition, such as: congenital rubella (P35.0) | underlying disease, such as: brucellosis (A23.0-A23.9) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources