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Compare/E09.649 vs E16.0

E09.649 vs E16.0

E09.649 (Drug or chemical induced diabetes mellitus with hypoglycemia without coma) compared with E16.0 (Drug-induced hypoglycemia without coma), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. E16.0 carries an Excludes1 note covering E09.649: “diabetes with hypoglycemia without coma (E09.649)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E09.649Drug or chemical induced diabetes mellitus with hypoglycemia without comaE16.0Drug-induced hypoglycemia without coma
Billing statusBillableBillable
ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)
DefinitionDrug or chemical induced diabetes mellitus with hypoglycemia without coma is a billable ICD-10-CM diagnosis code (E09.649).Drug-induced hypoglycemia without coma is a billable ICD-10-CM diagnosis code (E16.0).
Use additional code
code for hypoglycemia level, if applicable (E16.A-)
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code to identify control using:
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code for hypoglycemia level, if applicable (E16.A-)
Code first
poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources