E21.0 vs E83.5
E21.0 (Primary hyperparathyroidism) compared with E83.5 (Disorders of calcium metabolism), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. E83.5 carries an Excludes1 note covering E21.0: “hyperparathyroidism (E21.0-E21.3)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
No — do not report together. E83.5 carries an Excludes1 note covering E21.0: “parathyroid disorders (E20-E21)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| E21.0Primary hyperparathyroidism | E83.5Disorders of calcium metabolism | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) |
| Definition | Primary hyperparathyroidism is a billable ICD-10-CM diagnosis code (E21.0). | Disorders of calcium metabolism is a non-billable ICD-10-CM category code (E83.5). |
| Includes | Hyperplasia of parathyroid Osteitis fibrosa cystica generalisata [von Recklinghausen's disease of bone] | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources