E22.0 vs M26.0
E22.0 (Acromegaly and pituitary gigantism) compared with M26.0 (Major anomalies of jaw size), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. M26.0 carries an Excludes1 note covering E22.0: “acromegaly (E22.0)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| E22.0Acromegaly and pituitary gigantism | M26.0Major anomalies of jaw size | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | M00-M99 — Diseases of the Musculoskeletal System and Connective Tissue (M00-M99) |
| Definition | Acromegaly and pituitary gigantism is a billable ICD-10-CM diagnosis code (E22.0). | Major anomalies of jaw size is a non-billable ICD-10-CM category code (M26.0). |
| Includes | Overproduction of growth hormone | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources