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Compare/E25.0 vs E85

E25.0 vs E85

E25.0 (Congenital adrenogenital disorders associated with enzyme deficiency) compared with E85 (Amyloidosis), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. E85 carries an Excludes1 note covering E25.0: “congenital adrenal hyperplasia (E25.0)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E25.0Congenital adrenogenital disorders associated with enzyme deficiencyE85Amyloidosis
Billing statusBillableNon-billable header

Report instead: E85.0, E85.1, E85.2, E85.3, E85.4

ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)
DefinitionCongenital adrenogenital disorders associated with enzyme deficiency is a billable ICD-10-CM diagnosis code (E25.0).Amyloidosis is a non-billable ICD-10-CM category code (E85).
Includes
adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
Female adrenal pseudohermaphroditism
Female heterosexual precocious pseudopuberty
Male isosexual precocious pseudopuberty

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources