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Compare/E29.1 vs E72

E29.1 vs E72

E29.1 (Testicular hypofunction) compared with E72 (Other disorders of amino-acid metabolism), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. E72 carries an Excludes1 note covering E29.1: “5-alpha-reductase deficiency (E29.1)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E29.1Testicular hypofunctionE72Other disorders of amino-acid metabolism
Billing statusBillableNon-billable header

Report instead: E72.00, E72.01, E72.02, E72.03, E72.04

ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)
DefinitionTesticular hypofunction is a billable ICD-10-CM diagnosis code (E29.1).Other disorders of amino-acid metabolism is a non-billable ICD-10-CM category code (E72).
Includes
Defective biosynthesis of testicular androgen NOS
5-Alpha-reductase deficiency (with male pseudohermaphroditism)
Testicular hypogonadism NOS
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources