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E72.54 vs R82.992

E72.54 (Secondary hyperoxaluria) compared with R82.992 (Hyperoxaluria), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. R82.992 carries an Excludes1 note covering E72.54: “secondary hyperoxaluria (E72.54-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

No — do not report together. R82.992 carries an Excludes1 note covering E72.54: “specific findings indicating disorder of amino-acid metabolism (E70-E72)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E72.54Secondary hyperoxaluriaR82.992Hyperoxaluria
Billing statusNon-billable header

Report instead: E72.540, E72.541, E72.548, E72.549

Billable
ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)
DefinitionSecondary hyperoxaluria is a non-billable ICD-10-CM category code (E72.54).Hyperoxaluria is a billable ICD-10-CM diagnosis code (R82.992).
Includes
chromoabnormalities in urine
Use additional code
code to identify any retained foreign body, if applicable (Z18.-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources