E80.5 vs P58
E80.5 (Crigler-Najjar syndrome) compared with P58 (Neonatal jaundice due to other excessive hemolysis), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. P58 carries an Excludes1 note covering E80.5: “Crigler-Najjar syndrome (E80.5)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| E80.5Crigler-Najjar syndrome | P58Neonatal jaundice due to other excessive hemolysis | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | P00-P96 — Certain Conditions Originating in the Perinatal Period (P00-P96) |
| Definition | Crigler-Najjar syndrome is a billable ICD-10-CM diagnosis code (E80.5). | Neonatal jaundice due to other excessive hemolysis is a non-billable ICD-10-CM category code (P58). |
| Includes | defects of catalase and peroxidase | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources