E83.111 vs T80.49XD
E83.111 (Hemochromatosis due to repeated red blood cell transfusions) compared with T80.49XD (Other Rh incompatibility reaction due to transfusion of blood or blood products, subsequent encounter), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. T80.49XD carries an Excludes2 note covering E83.111: “transfusion (red blood cell) associated hemochromatosis (E83.111)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| E83.111Hemochromatosis due to repeated red blood cell transfusions | T80.49XDOther Rh incompatibility reaction due to transfusion of blood or blood products, subsequent encounter | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Hemochromatosis due to repeated red blood cell transfusions is a billable ICD-10-CM diagnosis code (E83.111). | Other Rh incompatibility reaction due to transfusion of blood or blood products, subsequent encounter is a billable ICD-10-CM diagnosis code (T80.49D). |
| 7th character | — | The appropriate 7th character is to be added to each code from category T80 |
| Includes | Iron overload due to repeated red blood cell transfusions Transfusion (red blood cell) associated hemochromatosis | complications following perfusion Delayed serologic transfusion reaction (DSTR) from Rh incompatibility Other reaction to Rh incompatible blood transfusion |
| Use additional code | — | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources