E83.111 (Hemochromatosis due to repeated red blood cell transfusions) compared with T80.52XA (Anaphylactic reaction due to vaccination, initial encounter), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Distinct conditions — both may be reported.
“transfusion (red blood cell) associated hemochromatosis (E83.111)”
An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.
Source: CMS ICD-10-CM tabular instructional notes
Yes, when both are documented. T80.52XA carries an Excludes2 note covering E83.111: “transfusion (red blood cell) associated hemochromatosis (E83.111)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
| E83.111Hemochromatosis due to repeated red blood cell transfusions | T80.52XAAnaphylactic reaction due to vaccination, initial encounter | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Hemochromatosis due to repeated red blood cell transfusions is a billable ICD-10-CM diagnosis code (E83.111). | Anaphylactic reaction due to vaccination, initial encounter is a billable ICD-10-CM diagnosis code (T80.52A). |
| 7th character | — | The appropriate 7th character is to be added to each code from category T80 |
| Includes | Iron overload due to repeated red blood cell transfusions Transfusion (red blood cell) associated hemochromatosis | complications following perfusion |
| Use additional code | — | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources