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Compare/E88.1 vs K90.81

E88.1 vs K90.81

E88.1 (Lipodystrophy, not elsewhere classified) compared with K90.81 (Whipple's disease), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. E88.1 carries an Excludes1 note covering K90.81: “Whipple's disease (K90.81)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E88.1Lipodystrophy, not elsewhere classifiedK90.81Whipple's disease
Billing statusNon-billable header

Report instead: E88.10, E88.11, E88.12, E88.13, E88.14

Billable
ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)K00-K95 — Diseases of the Digestive System (K00-K95)
DefinitionLipodystrophy, not elsewhere classified is a non-billable ICD-10-CM category code (E88.1).Whipple's disease is a billable ICD-10-CM diagnosis code (K90.81).
Use additional code
codes for associated conditions

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources