E88.4 vs Q93

E88.4 (Mitochondrial metabolism disorders) compared with Q93 (Monosomies and deletions from the autosomes, not elsewhere classified), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. Q93 carries an Excludes2 note covering E88.4: “mitochondrial metabolic disorders (E88.4-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

	E88.4Mitochondrial metabolism disorders	Q93Monosomies and deletions from the autosomes, not elsewhere classified
Billing status	Non-billable header Report instead: E88.40, E88.41, E88.42, E88.43, E88.49	Non-billable header Report instead: Q93.0, Q93.1, Q93.2, Q93.3, Q93.4
Classification	E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)	Q00-Q99 — Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-Q99)
Definition	Mitochondrial metabolism disorders is a non-billable ICD-10-CM category code (E88.4).	Monosomies and deletions from the autosomes, not elsewhere classified is a non-billable ICD-10-CM category code (Q93).
Use additional code	codes for associated conditions	—

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Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources