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Compare/E88.4 vs Q95

E88.4 vs Q95

E88.4 (Mitochondrial metabolism disorders) compared with Q95 (Balanced rearrangements and structural markers, not elsewhere classified), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. Q95 carries an Excludes2 note covering E88.4: “mitochondrial metabolic disorders (E88.4-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

E88.4Mitochondrial metabolism disordersQ95Balanced rearrangements and structural markers, not elsewhere classified
Billing statusNon-billable header

Report instead: E88.40, E88.41, E88.42, E88.43, E88.49

Non-billable header

Report instead: Q95.0, Q95.1, Q95.2, Q95.3, Q95.5

ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)Q00-Q99 — Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-Q99)
DefinitionMitochondrial metabolism disorders is a non-billable ICD-10-CM category code (E88.4).Balanced rearrangements and structural markers, not elsewhere classified is a non-billable ICD-10-CM category code (Q95).
Includes
Robertsonian and balanced reciprocal translocations and insertions
Use additional code
codes for associated conditions

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources