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F25 vs F32.3

F25 (Schizoaffective disorders) compared with F32.3 (Major depressive disorder, single episode, severe with psychotic features), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. F25 carries an Excludes1 note covering F32.3: “mood [affective] disorders with psychotic symptoms (F30.2, F31.2, F31.5, F31.64, F32.3, F33.3)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

F25Schizoaffective disordersF32.3Major depressive disorder, single episode, severe with psychotic features
Billing statusNon-billable header

Report instead: F25.0, F25.1, F25.8, F25.9

Billable
ClassificationF01-F99 — Mental, Behavioral and Neurodevelopmental Disorders (F01-F99)F01-F99 — Mental, Behavioral and Neurodevelopmental Disorders (F01-F99)
DefinitionSchizoaffective disorders is a non-billable ICD-10-CM category code (F25).Major depressive disorder, single episode, severe with psychotic features is a billable ICD-10-CM diagnosis code (F32.3).
Includes
single episode of agitated depression
single episode of depressive reaction
single episode of major depression
single episode of psychogenic depression

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources