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Compare/F25 vs F33.3

F25 vs F33.3

F25 (Schizoaffective disorders) compared with F33.3 (Major depressive disorder, recurrent, severe with psychotic symptoms), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. F25 carries an Excludes1 note covering F33.3: “mood [affective] disorders with psychotic symptoms (F30.2, F31.2, F31.5, F31.64, F32.3, F33.3)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

F25Schizoaffective disordersF33.3Major depressive disorder, recurrent, severe with psychotic symptoms
Billing statusNon-billable header

Report instead: F25.0, F25.1, F25.8, F25.9

Billable
ClassificationF01-F99 — Mental, Behavioral and Neurodevelopmental Disorders (F01-F99)F01-F99 — Mental, Behavioral and Neurodevelopmental Disorders (F01-F99)
DefinitionSchizoaffective disorders is a non-billable ICD-10-CM category code (F25).Major depressive disorder, recurrent, severe with psychotic symptoms is a billable ICD-10-CM diagnosis code (F33.3).
Includes
recurrent episodes of depressive reaction
recurrent episodes of endogenous depression
recurrent episodes of major depression
recurrent episodes of psychogenic depression

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources