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F33.3 vs F53

F33.3 (Major depressive disorder, recurrent, severe with psychotic symptoms) compared with F53 (Mental and behavioral disorders associated with the puerperium, not elsewhere classified), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. F53 carries an Excludes1 note covering F33.3: “mood disorders with psychotic features (F30.2, F31.2, F31.5, F31.64, F32.3, F33.3)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

F33.3Major depressive disorder, recurrent, severe with psychotic symptomsF53Mental and behavioral disorders associated with the puerperium, not elsewhere classified
Billing statusBillableNon-billable header

Report instead: F53.0, F53.1

ClassificationF01-F99 — Mental, Behavioral and Neurodevelopmental Disorders (F01-F99)F01-F99 — Mental, Behavioral and Neurodevelopmental Disorders (F01-F99)
DefinitionMajor depressive disorder, recurrent, severe with psychotic symptoms is a billable ICD-10-CM diagnosis code (F33.3).Mental and behavioral disorders associated with the puerperium, not elsewhere classified is a non-billable ICD-10-CM category code (F53).
Includes
recurrent episodes of depressive reaction
recurrent episodes of endogenous depression
recurrent episodes of major depression
recurrent episodes of psychogenic depression

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources