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I21 vs I24.1

I21 (Acute myocardial infarction) compared with I24.1 (Dressler's syndrome), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. I21 carries an Excludes2 note covering I24.1: “postmyocardial infarction syndrome (I24.1)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

I21Acute myocardial infarctionI24.1Dressler's syndrome
Billing statusNon-billable header

Report instead: I21.01, I21.02, I21.09, I21.11, I21.19

Billable
ClassificationI00-I99 — Diseases of the Circulatory System (I00-I99)I00-I99 — Diseases of the Circulatory System (I00-I99)
DefinitionAcute myocardial infarction is a non-billable ICD-10-CM category code (I21).Dressler's syndrome is a billable ICD-10-CM diagnosis code (I24.1).
Includes
cardiac infarction
coronary (artery) embolism
coronary (artery) occlusion
coronary (artery) rupture
Postmyocardial infarction syndrome
Use additional code
code, if applicable, to identify:
exposure to environmental tobacco smoke (Z77.22)
history of tobacco dependence (Z87.891)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources