I21 vs I25.2
I21 (Acute myocardial infarction) compared with I25.2 (Old myocardial infarction), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. I21 carries an Excludes2 note covering I25.2: “old myocardial infarction (I25.2)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| I21Acute myocardial infarction | I25.2Old myocardial infarction | |
|---|---|---|
| Billing status | Non-billable header | Billable |
| Classification | I00-I99 — Diseases of the Circulatory System (I00-I99) | I00-I99 — Diseases of the Circulatory System (I00-I99) |
| Definition | Acute myocardial infarction is a non-billable ICD-10-CM category code (I21). | Old myocardial infarction is a billable ICD-10-CM diagnosis code (I25.2). |
| Includes | cardiac infarction coronary (artery) embolism coronary (artery) occlusion coronary (artery) rupture | Healed myocardial infarction Past myocardial infarction diagnosed by ECG or other investigation, but currently presenting no symptoms |
| Use additional code | code, if applicable, to identify: exposure to environmental tobacco smoke (Z77.22) history of tobacco dependence (Z87.891) | code to identify: chronic total occlusion of coronary artery (I25.82) exposure to environmental tobacco smoke (Z77.22) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources