I21 vs I74.8
I21 (Acute myocardial infarction) compared with I74.8 (Embolism and thrombosis of other arteries), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. I74.8 carries an Excludes2 note covering I21: “coronary embolism and thrombosis (I21-I25)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| I21Acute myocardial infarction | I74.8Embolism and thrombosis of other arteries | |
|---|---|---|
| Billing status | Non-billable header | Billable |
| Classification | I00-I99 — Diseases of the Circulatory System (I00-I99) | I00-I99 — Diseases of the Circulatory System (I00-I99) |
| Definition | Acute myocardial infarction is a non-billable ICD-10-CM category code (I21). | Embolism and thrombosis of other arteries is a billable ICD-10-CM diagnosis code (I74.8). |
| Includes | cardiac infarction coronary (artery) embolism coronary (artery) occlusion coronary (artery) rupture | embolic infarction embolic occlusion thrombotic infarction thrombotic occlusion |
| Use additional code | code, if applicable, to identify: exposure to environmental tobacco smoke (Z77.22) history of tobacco dependence (Z87.891) | — |
| Code first | — | embolism and thrombosis complicating abortion or ectopic or molar pregnancy (O00-O07, O08.2) embolism and thrombosis complicating pregnancy, childbirth and the puerperium (O88.-) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources