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I21 vs I82.56

I21 (Acute myocardial infarction) compared with I82.56 (Chronic embolism and thrombosis of calf muscular vein), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. I82.56 carries an Excludes2 note covering I21: “coronary (I21-I25)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

I21Acute myocardial infarctionI82.56Chronic embolism and thrombosis of calf muscular vein
Billing statusNon-billable header

Report instead: I21.01, I21.02, I21.09, I21.11, I21.19

Non-billable header

Report instead: I82.561, I82.562, I82.563, I82.569

ClassificationI00-I99 — Diseases of the Circulatory System (I00-I99)I00-I99 — Diseases of the Circulatory System (I00-I99)
DefinitionAcute myocardial infarction is a non-billable ICD-10-CM category code (I21).Chronic embolism and thrombosis of calf muscular vein is a non-billable ICD-10-CM category code (I82.56).
Includes
cardiac infarction
coronary (artery) embolism
coronary (artery) occlusion
coronary (artery) rupture
Chronic embolism and thrombosis of calf muscular vein NOS
Chronic embolism and thrombosis of gastrocnemial vein
Chronic embolism and thrombosis of soleal vein
Use additional code
code, if applicable, to identify:
exposure to environmental tobacco smoke (Z77.22)
history of tobacco dependence (Z87.891)
code, if applicable, for associated long-term (current) use of anticoagulants (Z79.01)
Code first
venous embolism and thrombosis complicating:
abortion, ectopic or molar pregnancy (O00-O07, O08.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources