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I25.10 vs I25.7

I25.10 (Atherosclerotic heart disease of native coronary artery without angina pectoris) compared with I25.7 (Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris), from the official CMS tabular data.

Summary

These codes can be reported together when both conditions are documented, because I25.10 lists I25.7 under Excludes2, which marks them as distinct conditions.

Official rule
What is different?

Title wording and billing status.The titles share “angina pectoris”; I25.10 says “Atherosclerotic heart disease of native coronary artery without” where I25.7 says “Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with”. I25.7 is a non-billable header; I25.10 is billable.

Registry fact

Can these codes be reported together?

Yes, when both are documented.I25.10 lists I25.7 under Excludes2: “atherosclerosis of coronary artery bypass graft(s) and transplanted heart (I25.7-)”. Excludes2 marks distinct conditions that may both be reported when both are documented.

Official ruleGuide: Excludes1 vs Excludes2

Is there an Excludes1 relationship?

None.Neither entry carries an Excludes1 note that names the other code. I25.7 carries 3 Excludes1 notes covering other codes; the side-by-side table quotes them.

Official rule

Is there an Excludes2 relationship?

Yes.I25.10’s tabular entry: “atherosclerosis of coronary artery bypass graft(s) and transplanted heart (I25.7-)”. The note covers I25.7.

Official ruleGuide: Excludes1 vs Excludes2

Is one more specific?

No.Neither is a subdivision of the other, and neither title is the unspecified form; they describe different conditions within category I25.

Registry fact

Is one a parent or header code?

One is a header.I25.7 is a non-billable header, but I25.10 is not one of its subdivisions.

Registry fact

Are there sequencing instructions?

None.Neither entry carries a Code First or Use Additional Code note that names the other.

Official rule

Are there other coding relationships?

None found.No laterality, encounter-phase, Table of Neoplasms, Table of Drugs and Chemicals, or history-versus-active-disease relationship links these codes.

MedCoder-derived

Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels

Can these codes be reported together?

Informational

Excludes2 relationship

I25.10
Atherosclerotic heart disease of native coronary artery without angina pectoris
↔
I25.7
Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris

What we found

Yes, when both are documented.I25.10 carries an Excludes2 note covering I25.7: “atherosclerosis of coronary artery bypass graft(s) and transplanted heart (I25.7-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

What to review

Report both only when the documentation supports both conditions; otherwise report the one documented.

Guide: Excludes1 vs Excludes2Check these on a claim

Why it matters

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source / rule

CMS ICD-10-CM tabular instructional notes

Official guidance behind these answers

  • Section I.A.12.b — Excludes2 · applies to: Excludes2

    A type 2 Excludes note represents “Not included here.” An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

    ICD-10-CM Official Guidelines FY2026

Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum

Side by side

I25.10Atherosclerotic heart disease of native coronary artery without angina pectorisI25.7Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris
Billing statusBillableNon-billable header

Report instead: I25.700, I25.701, I25.702, I25.708, I25.709

ClassificationI00-I99 — Diseases of the Circulatory System (I00-I99)I00-I99 — Diseases of the Circulatory System (I00-I99)
DefinitionAtherosclerotic heart disease of native coronary artery without angina pectoris is a billable ICD-10-CM diagnosis code (I25.10).Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris is a non-billable ICD-10-CM category code (I25.7).
Includes
Atherosclerotic heart disease NOS
—
Excludes1—
atherosclerosis of bypass graft(s) of transplanted heart without angina pectoris (I25.812)
atherosclerosis of coronary artery bypass graft(s) without angina pectoris (I25.810)
atherosclerosis of native coronary artery of transplanted heart without angina pectoris (I25.811)
Excludes2
atheroembolism (I75.-)
atherosclerosis of coronary artery bypass graft(s) and transplanted heart (I25.7-)
non-ischemic myocardial injury (I5A)
non-ischemic myocardial injury (I5A)
Use additional code
code, if applicable, to identify:
coronary atherosclerosis due to calcified coronary lesion (I25.84)
coronary atherosclerosis due to lipid rich plaque (I25.83)
code, if applicable, to identify:
coronary atherosclerosis due to calcified coronary lesion (I25.84)
coronary atherosclerosis due to lipid rich plaque (I25.83)
Code also
the presence of hypertension (I10-I1A)
the presence of hypertension (I10-I1A)

Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on.

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Derived from the official CMS ICD-10-CM tabular data (FY2026). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources