I25.10 vs I25.81
I25.10 (Atherosclerotic heart disease of native coronary artery without angina pectoris) compared with I25.81 (Atherosclerosis of other coronary vessels without angina pectoris), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. I25.81 carries an Excludes2 note covering I25.10: “atherosclerotic heart disease of native coronary artery without angina pectoris (I25.10)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| I25.10Atherosclerotic heart disease of native coronary artery without angina pectoris | I25.81Atherosclerosis of other coronary vessels without angina pectoris | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | I00-I99 — Diseases of the Circulatory System (I00-I99) | I00-I99 — Diseases of the Circulatory System (I00-I99) |
| Definition | Atherosclerotic heart disease of native coronary artery without angina pectoris is a billable ICD-10-CM diagnosis code (I25.10). | Atherosclerosis of other coronary vessels without angina pectoris is a non-billable ICD-10-CM category code (I25.81). |
| Includes | Atherosclerotic heart disease NOS | — |
| Use additional code | code, if applicable, to identify: coronary atherosclerosis due to calcified coronary lesion (I25.84) coronary atherosclerosis due to lipid rich plaque (I25.83) | code, if applicable, to identify: coronary atherosclerosis due to calcified coronary lesion (I25.84) coronary atherosclerosis due to lipid rich plaque (I25.83) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources