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I27.0 vs I27.21

I27.0 (Primary pulmonary hypertension) compared with I27.21 (Secondary pulmonary arterial hypertension), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. I27.0 carries an Excludes1 note covering I27.21: “secondary pulmonary arterial hypertension (I27.21)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

I27.0Primary pulmonary hypertensionI27.21Secondary pulmonary arterial hypertension
Billing statusBillableBillable
ClassificationI00-I99 — Diseases of the Circulatory System (I00-I99)I00-I99 — Diseases of the Circulatory System (I00-I99)
DefinitionPrimary pulmonary hypertension is a billable ICD-10-CM diagnosis code (I27.0).Secondary pulmonary arterial hypertension is a billable ICD-10-CM diagnosis code (I27.21).
Includes
Heritable pulmonary arterial hypertension
Idiopathic pulmonary arterial hypertension
Primary group 1 pulmonary hypertension
Primary pulmonary arterial hypertension
(Associated) (drug-induced) (toxin-induced) pulmonary arterial hypertension NOS
(Associated) (drug-induced) (toxin-induced) (secondary) group 1 pulmonary hypertension

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources