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K21.00 vs P78.83

K21.00 (Gastro-esophageal reflux disease with esophagitis, without bleeding) compared with P78.83 (Newborn esophageal reflux), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. K21.00 carries an Excludes1 note covering P78.83: “newborn esophageal reflux (P78.83)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

K21.00Gastro-esophageal reflux disease with esophagitis, without bleedingP78.83Newborn esophageal reflux
Billing statusBillableBillable
ClassificationK00-K95 — Diseases of the Digestive System (K00-K95)P00-P96 — Certain Conditions Originating in the Perinatal Period (P00-P96)
DefinitionGastro-esophageal reflux disease with esophagitis, without bleeding is a billable ICD-10-CM diagnosis code (K21.00).Newborn esophageal reflux is a billable ICD-10-CM diagnosis code (P78.83).
Includes
Reflux esophagitis
Neonatal esophageal reflux

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources