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L25.1 vs L27.1

L25.1 (Unspecified contact dermatitis due to drugs in contact with skin) compared with L27.1 (Localized skin eruption due to drugs and medicaments taken internally), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. L25.1 carries an Excludes2 note covering L27.1: “dermatitis due to ingested drugs and medicaments (L27.0-L27.1)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. L25.1 carries an Excludes2 note covering L27.1: “dermatitis due to ingested substances (L27.-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. L27.1 carries an Excludes2 note covering L25.1: “contact dermatitis (L23-L25)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

L25.1Unspecified contact dermatitis due to drugs in contact with skinL27.1Localized skin eruption due to drugs and medicaments taken internally
Billing statusBillableBillable
ClassificationL00-L99 — Diseases of the Skin and Subcutaneous Tissue (L00-L99)L00-L99 — Diseases of the Skin and Subcutaneous Tissue (L00-L99)
DefinitionUnspecified contact dermatitis due to drugs in contact with skin is a billable ICD-10-CM diagnosis code (L25.1).Localized skin eruption due to drugs and medicaments taken internally is a billable ICD-10-CM diagnosis code (L27.1).
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources