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M48.4 vs S22.0

M48.4 (Fatigue fracture of vertebra) compared with S22.0 (Fracture of thoracic vertebra), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. M48.4 carries an Excludes1 note covering S22.0: “traumatic fracture of vertebrae (S12.0-S12.3-, S22.0-, S32.0-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

M48.4Fatigue fracture of vertebraS22.0Fracture of thoracic vertebra
Billing statusNon-billable header

Report instead: M48.40XA, M48.40XD, M48.40XG, M48.40XS, M48.41XA

Non-billable header

Report instead: S22.000A, S22.000B, S22.000D, S22.000G, S22.000K

ClassificationM00-M99 — Diseases of the Musculoskeletal System and Connective Tissue (M00-M99)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionFatigue fracture of vertebra is a non-billable ICD-10-CM category code (M48.4).Fracture of thoracic vertebra is a non-billable ICD-10-CM category code (S22.0).
7th characterThe appropriate 7th character is to be added to each code from subcategory M48.4:The appropriate 7th character is to be added to each code from category S22
Includes
Stress fracture of vertebra
fracture of thoracic neural arch
fracture of thoracic spinous process
fracture of thoracic transverse process
fracture of thoracic vertebra
Code first
, if applicable, spinal cord injury (S24.0-, S24.1-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources