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M80.8 vs N99.821

M80.8 (Other osteoporosis with current pathological fracture) compared with N99.821 (Postprocedural hemorrhage of a genitourinary system organ or structure following other procedure), from the official CMS tabular data.

Summary

These codes can be reported together when both conditions are documented, because N99.821 lists M80.8 under Excludes2, which marks them as distinct conditions.

Official rule
What is different?

The conditions named, billing status and chapter.M80.8 is “Other osteoporosis with current pathological fracture”; N99.821 is “Postprocedural hemorrhage of a genitourinary system organ or structure following other procedure”. M80.8 is a non-billable header; N99.821 is billable. M80.8 sits in M00-M99 — Diseases of the Musculoskeletal System and Connective Tissue (M00-M99); N99.821 in N00-N99 — Diseases of the Genitourinary System (N00-N99).

Registry fact

Can these codes be reported together?

Yes, when both are documented.N99.821 lists M80.8 under Excludes2: “postoophorectomy osteoporosis with current pathological fracture (M80.8-)”. Excludes2 marks distinct conditions that may both be reported when both are documented.

Official ruleGuide: Excludes1 vs Excludes2

Is there an Excludes1 relationship?

None.Neither entry carries an Excludes1 note that names the other code. M80.8 carries 3 Excludes1 notes covering other codes; the side-by-side table quotes them.

Official rule

Is there an Excludes2 relationship?

Yes.N99.821’s tabular entry: “postoophorectomy osteoporosis with current pathological fracture (M80.8-)”. The note covers M80.8.

Official ruleGuide: Excludes1 vs Excludes2

Is one more specific?

Not comparable.The codes sit in different categories; specificity is only comparable within one category.

Is one a parent or header code?

One is a header.M80.8 is a non-billable header, but N99.821 is not one of its subdivisions.

Registry fact

Are there sequencing instructions?

None.Neither entry carries a Code First or Use Additional Code note that names the other.

Official rule

Are there other coding relationships?

None found.No laterality, encounter-phase, Table of Neoplasms, Table of Drugs and Chemicals, or history-versus-active-disease relationship links these codes.

MedCoder-derived

Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels

Can these codes be reported together?

Informational

Excludes2 relationship

N99.821
Postprocedural hemorrhage of a genitourinary system organ or structure following other procedure
↔
M80.8
Other osteoporosis with current pathological fracture

What we found

Yes, when both are documented.N99.821 carries an Excludes2 note covering M80.8: “postoophorectomy osteoporosis with current pathological fracture (M80.8-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

What to review

Report both only when the documentation supports both conditions; otherwise report the one documented.

Guide: Excludes1 vs Excludes2Check these on a claim

Why it matters

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source / rule

CMS ICD-10-CM tabular instructional notes

Official guidance behind these answers

  • Section I.A.12.b — Excludes2 · applies to: Excludes2

    A type 2 Excludes note represents “Not included here.” An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

    ICD-10-CM Official Guidelines FY2026

Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum

Side by side

M80.8Other osteoporosis with current pathological fractureN99.821Postprocedural hemorrhage of a genitourinary system organ or structure following other procedure
Billing statusNon-billable header

Report instead: M80.80XA, M80.80XD, M80.80XG, M80.80XK, M80.80XP

Billable
ClassificationM00-M99 — Diseases of the Musculoskeletal System and Connective Tissue (M00-M99)N00-N99 — Diseases of the Genitourinary System (N00-N99)
DefinitionOther osteoporosis with current pathological fracture is a non-billable ICD-10-CM category code (M80.8).Postprocedural hemorrhage of a genitourinary system organ or structure following other procedure is a billable ICD-10-CM diagnosis code (N99.821).
7th characterThe appropriate 7th character is to be added to each code from category M80:—
Includes
osteoporosis with current fragility fracture
Drug-induced osteoporosis with current pathological fracture
Idiopathic osteoporosis with current pathological fracture
Osteoporosis of disuse with current pathological fracture
—
Excludes1
collapsed vertebra NOS (M48.5)
pathological fracture NOS (M84.4)
wedging of vertebra NOS (M48.5)
—
Excludes2
personal history of (healed) osteoporosis fracture (Z87.310)
irradiation cystitis (N30.4-)
postoophorectomy osteoporosis with current pathological fracture (M80.8-)
postoophorectomy osteoporosis without current pathological fracture (M81.8)
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code to identify major osseous defect, if applicable (M89.7-)
—

Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on.

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Derived from the official CMS ICD-10-CM tabular data (FY2027). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources