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Compare/O29.3 vs T42

O29.3 vs T42

O29.3 (Toxic reaction to local anesthesia during pregnancy) compared with T42 (Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. T42 carries an Excludes1 note covering O29.3: “toxic reaction to local anesthesia in pregnancy (O29.3-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

O29.3Toxic reaction to local anesthesia during pregnancyT42Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs
Billing statusNon-billable header

Report instead: O29.3X1, O29.3X2, O29.3X3, O29.3X9

Non-billable header

Report instead: T42.0X1A, T42.0X1D, T42.0X1S, T42.0X2A, T42.0X2D

ClassificationO00-O9A — Pregnancy, Childbirth and the Puerperium (O00-O9A)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionToxic reaction to local anesthesia during pregnancy is a non-billable ICD-10-CM category code (O29.3).Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs is a non-billable ICD-10-CM category code (T42).
7th characterThe appropriate 7th character is to be added to each code from category T42
Includes
maternal complications arising from the administration of a general, regional or local anesthetic, analgesic or other sedation during pregnancy
adverse effect of correct substance properly administered
poisoning by overdose of substance
poisoning by wrong substance given or taken in error
underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Use additional code
code, if necessary, to identify the complication
code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
Code first
, for adverse effects, the nature of the adverse effect, such as:
adverse effect NOS (T88.7)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources