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Compare/P22.0 vs P28.5

P22.0 vs P28.5

P22.0 (Respiratory distress syndrome of newborn) compared with P28.5 (Respiratory failure of newborn), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. P22.0 carries an Excludes2 note covering P28.5: “respiratory failure of newborn NOS (P28.5)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. P28.5 carries an Excludes2 note covering P22.0: “respiratory distress of newborn (P22.0)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

P22.0Respiratory distress syndrome of newbornP28.5Respiratory failure of newborn
Billing statusBillableBillable
ClassificationP00-P96 — Certain Conditions Originating in the Perinatal Period (P00-P96)P00-P96 — Certain Conditions Originating in the Perinatal Period (P00-P96)
DefinitionRespiratory distress syndrome of newborn is a billable ICD-10-CM diagnosis code (P22.0).Respiratory failure of newborn is a billable ICD-10-CM diagnosis code (P28.5).
Includes
Cardiorespiratory distress syndrome of newborn
Hyaline membrane disease
Idiopathic respiratory distress syndrome [IRDS or RDS] of newborn
Pulmonary hypoperfusion syndrome

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources