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P74.0 vs P74.421

P74.0 (Late metabolic acidosis of newborn) compared with P74.421 (Hyperchloremia of newborn), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. P74.421 carries an Excludes2 note covering P74.0: “late metabolic acidosis of the newborn (P74.0)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

P74.0Late metabolic acidosis of newbornP74.421Hyperchloremia of newborn
Billing statusBillableBillable
ClassificationP00-P96 — Certain Conditions Originating in the Perinatal Period (P00-P96)P00-P96 — Certain Conditions Originating in the Perinatal Period (P00-P96)
DefinitionLate metabolic acidosis of newborn is a billable ICD-10-CM diagnosis code (P74.0).Hyperchloremia of newborn is a billable ICD-10-CM diagnosis code (P74.421).
Includes
transitory endocrine and metabolic disturbances caused by the infant's response to maternal endocrine and metabolic factors, or its adjustment to extrauterine environment
transitory endocrine and metabolic disturbances caused by the infant's response to maternal endocrine and metabolic factors, or its adjustment to extrauterine environment
Hyperchloremic metabolic acidosis

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources