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Compare/R16 vs R39

R16 vs R39

R16 (Hepatomegaly and splenomegaly, not elsewhere classified) compared with R39 (Other and unspecified symptoms and signs involving the genitourinary system), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. R16 carries an Excludes2 note covering R39: “signs and symptoms involving the urinary system (R30-R39)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

R16Hepatomegaly and splenomegaly, not elsewhere classifiedR39Other and unspecified symptoms and signs involving the genitourinary system
Billing statusNon-billable header

Report instead: R16.0, R16.1, R16.2

Non-billable header

Report instead: R39.0, R39.11, R39.12, R39.13, R39.14

ClassificationR00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)
DefinitionHepatomegaly and splenomegaly, not elsewhere classified is a non-billable ICD-10-CM category code (R16).Other and unspecified symptoms and signs involving the genitourinary system is a non-billable ICD-10-CM category code (R39).

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources